Figure 4. CRF2 receptor binding in alcohol-naïve iP and iNP rats.
Characterization of CRF2 receptor binding was determined by [125I]-Tyr0-sauvagine affinity in frontal cortex homogenates from naïve iP and iNP rats. The graph depicts the competition profile in the presence of increasing concentrations of Astressin 2B. Each data point represents the mean ± SEM of eight separate experiments performed in duplicate.