Table 7.
Assay results for the determination of LEV and AMB in their prepared tablets
| Preparation |
Amount taken |
Amount found |
% Found |
Comparison method (35) |
||||
|---|---|---|---|---|---|---|---|---|
|
(μg/mL) |
(μg/mL) |
|||||||
| LEV | AMB | LEV | AMB | LEV | AMB | LEV | AMB | |
| Prepared tablet (250 mg LEV+60 mg AMB) |
5.0 |
6.0 |
25.1500 |
6.0020 |
100.60 |
100.04 |
100.10 |
100.68 |
| 20.0 |
1.2 |
4.9200 |
1.2010 |
98.40 |
100.12 |
99.02 |
103.35 |
|
| 25.0 |
4.8 |
19.7780 |
4.8250 |
98.89 |
102.00 |
98.16 |
101.60 |
|
|
|
|
|
|
|
100.20* |
100.72 |
99.09 |
101.88 |
|
± SD |
|
|
|
|
±1.64 |
±1.11 |
±0.97 |
±1.36 |
| % RSD |
|
|
|
|
1.63 |
1.10 |
0.98 |
1.33 |
| % Error |
|
|
|
|
0.94 |
0.64 |
0.57 |
0.77 |
| t |
|
|
|
|
0.233 |
1.143 |
|
|
| F | 1.418 | 1.495 | ||||||
N.B. Each result is the average of three separate determinations.
The values of tabulated t and F tests are 2.78 and 19.00 respectively at p = 0.05 [38].
Average LEV concentration found in tablet 250.50 mg and average AMB found 60.14 mg per tablet.