TABLE II. Frequency of histopathological aspects observed in the 40 cutaneous leishmaniasis (CL) and disseminated leishmaniasis (DL) biopsies.

	Epidermis							Dermis
	Fibrin crust	Hyperkeratosis	Acanthosis	Hydropic degeneration	Spongiosis	Exocytosis		Oedema	Granulation tissue	Granuloma	Giant cells	Lytic necrosis
LCL-L	30	80	100	80	80	50		90	90	80	20	50
LCL-E	30	90	100	80	50	60		100	90	30	20	10
DL-U	0	90	10	70	80	50		10	10	20	20	50
DL-P	40	70	70	50	50	50		10	10	30	30	50
p
LCL-L x LCL-E	NS	NS	NS	NS	0.0001	NS		NS	NS	0.0001	NS	0.0001
LCL-L x DL-U	0.0001	NS	NS	NS	NS	NS		0.0015	0.0015	0.0001	NS	NS
DL-U x DL-P	0.0001	0.0007	0.0001	0.0059	0.0001	NS		NS	NS	NS	NS	NS

DL-P: DL with papules; DL-U: DL with ulcers; LCL: localised CL; LCL-E: recent LCL; LCL-L: late LCL; NS: not significant.