TABLE II. Frequency of histopathological aspects observed in the 40 cutaneous leishmaniasis (CL) and disseminated leishmaniasis (DL) biopsies.
Epidermis | Dermis | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||||
Fibrin crust | Hyperkeratosis | Acanthosis | Hydropic degeneration | Spongiosis | Exocytosis | Oedema | Granulation tissue | Granuloma | Giant cells | Lytic necrosis | ||
LCL-L | 30 | 80 | 100 | 80 | 80 | 50 | 90 | 90 | 80 | 20 | 50 | |
LCL-E | 30 | 90 | 100 | 80 | 50 | 60 | 100 | 90 | 30 | 20 | 10 | |
DL-U | 0 | 90 | 10 | 70 | 80 | 50 | 10 | 10 | 20 | 20 | 50 | |
DL-P | 40 | 70 | 70 | 50 | 50 | 50 | 10 | 10 | 30 | 30 | 50 | |
p | ||||||||||||
LCL-L x LCL-E | NS | NS | NS | NS | 0.0001 | NS | NS | NS | 0.0001 | NS | 0.0001 | |
LCL-L x DL-U | 0.0001 | NS | NS | NS | NS | NS | 0.0015 | 0.0015 | 0.0001 | NS | NS | |
DL-U x DL-P | 0.0001 | 0.0007 | 0.0001 | 0.0059 | 0.0001 | NS | NS | NS | NS | NS | NS |
DL-P: DL with papules; DL-U: DL with ulcers; LCL: localised CL; LCL-E: recent LCL; LCL-L: late LCL; NS: not significant.