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. 2014 Mar 5;109(2):182–188. doi: 10.1590/0074-0276130344

TABLE I. Family structures for the 72 families with leprosy cases collected from Belém, state of Pará, Brazil.

Family structure Leprosy per se (n) Leprosy LL sub-type (n) Leprosy TT sub-type (n)
Families 72 72 72
Nuclear families 87 56a 48a
  with 1 affected sib 19 27 22
  with 2 affected sibs 50 25 17
  with 3 affected sibs 7 3 7
  with 4 affected sibs 5 1 1
  with 5 affected sibs 5 0 0
  with 6 affected sibs 0 0 1
  with 7 affected sibs 1 0 0
Affected offspring 192 90 87
Affected parents 41 25 10

Total affected individualsb 208c 109 93

Total individuals 372 372 372

a : 17 nuclear families contain both lepromatous (LL) and tuberculoid (TT) affected individuals, therefore number of LL + TT nuclear families do not add up to leprosy per se ; b : due to pedigree structure some individuals are classed as both sibs and parents in different nuclear families, therefore the total number of affected is not the sibs + parents; c : six leprosy per se individuals not classified as LL or TT, therefore numbers of affected children and parents for LL + TT do not add up to leprosy per se . Nuclear families with a single affected offspring were always part of an extended multicase pedigree.