TABLE I. Family structures for the 72 families with leprosy cases collected from Belém, state of Pará, Brazil.
Family structure | Leprosy per se (n) | Leprosy LL sub-type (n) | Leprosy TT sub-type (n) |
---|---|---|---|
Families | 72 | 72 | 72 |
Nuclear families | 87 | 56a | 48a |
with 1 affected sib | 19 | 27 | 22 |
with 2 affected sibs | 50 | 25 | 17 |
with 3 affected sibs | 7 | 3 | 7 |
with 4 affected sibs | 5 | 1 | 1 |
with 5 affected sibs | 5 | 0 | 0 |
with 6 affected sibs | 0 | 0 | 1 |
with 7 affected sibs | 1 | 0 | 0 |
Affected offspring | 192 | 90 | 87 |
Affected parents | 41 | 25 | 10 |
| |||
Total affected individualsb | 208c | 109 | 93 |
| |||
Total individuals | 372 | 372 | 372 |
a : 17 nuclear families contain both lepromatous (LL) and tuberculoid (TT) affected individuals, therefore number of LL + TT nuclear families do not add up to leprosy per se ; b : due to pedigree structure some individuals are classed as both sibs and parents in different nuclear families, therefore the total number of affected is not the sibs + parents; c : six leprosy per se individuals not classified as LL or TT, therefore numbers of affected children and parents for LL + TT do not add up to leprosy per se . Nuclear families with a single affected offspring were always part of an extended multicase pedigree.