TABLE IV. Robust case/pseudo-control (CPC) analysis for ERBB2 tagging single nucleotide polymorphisms (tag-SNPs) in primary families from the state of Pará, Brazil.
| SNP | Phenotype | Allele | # CPC sets | OR | 95% CI | p |
|---|---|---|---|---|---|---|
| rs2517956 | LL | G | 17 | 3.25 | 1.37-7.70 | 0.007 |
| rs2952156 | LL | A | 18 | 2.75 | 1.15-6.55 | 0.022 |
| rs1058808 | LL | C | 14 | 2.50 | 1.09-5.74 | 0.031 |
| rs2517956 | TT | G | 27 | 1.79 | 1.04-3.05 | 0.034 |
| rs2952156 | TT | A | 28 | 1.47 | 0.73-2.96 | 0.284 |
| rs1058808 | TT | C | 25 | 2.08 | 1.13-3.85 | 0.019 |
| rs2517956 | Leprosy per se | G | 47 | 2.22 | 1.37-3.59 | 0.001 |
| rs2952156 | Leprosy per se | A | 50 | 1.84 | 1.00-3.39 | 0.050 |
| rs1058808 | Leprosy per se | C | 39 | 2.18 | 1.28-3.74 | 0.004 |
robust CPC was used to analyse transmission of alleles at ERBB2 tag-SNPs (Table III) from heterozygous parents to lepromatous (LL), tuberculoid (TT) and leprosy per se individuals. CI: confidence interval; OR: odds ratio.