Table 2.
Gene expression in antrum and corpus tissue of Hp- individuals, for known antrum- and corpus-specific genes
| Tissue specificity | Cell type | Description | Symbol | ID | Fold difference 1 | p-value 2 |
|---|---|---|---|---|---|---|
|
Corpus |
ECL-cell |
Histidine decarboxylase |
HDC |
ILMN_98661 |
11 |
1.0 x10-4 |
| ECL/Parietal cell |
Gastrin receptor 1 |
CCKBR |
ILMN_9090 |
15 |
5.5 x 10-4 |
|
| Parietal Cell |
ATPase H+/K+ exchanging, beta |
ATP4B |
ILMN_12353 |
49 |
1.6 x 10-3 |
|
| Parietal Cell |
ATPase H+/K+ exchanging, alpha |
ATP4A |
ILMN_16471 |
45 |
4.5 x 10-5 |
|
| Parietal cell |
Gastric intrinsic factor |
GIF |
ILMN_18902 |
17 |
1.3 x 10-2 |
|
| A-like/Gr cell |
Ghrelin |
GHRL |
ILMN_19385 |
10 |
5.0 x 10-2 |
|
| Chief cell |
Pepsinogen |
PGA5 |
ILMN_23664 |
48 |
2.4 x 10-2 |
|
| Antrum | G-cell | Gastrin | GAST | ILMN_23553 | 848 | 2.8 x 10-5 |
1 Fold difference when comparing gene expression levels in corpus vs. antrum for corpus specific genes, and antrum vs. corpus for antrum-specific genes.
2 Antrum and corpus expression was compared using Student’s t-test; only values ≤ 0.05 are shown.