Table 1.

Summary of the findings in previous studies that investigated the effect of oxytocin in ASD

Study	Oxytocin application	Major findings
Hollandar et al. (2003) [21]	Intravanous	Reduced repetitive behaviors
Hollandar et al. (2007) [25]	Intravanous	Improved affective speech comprehension
Guastella et al. (2010) [23]	Intranasal (single dose)	Improved performance in Reading-the-Mind-in-the-Eyes Test
Andari et al. (2010) [22]	Intranasal (single dose)	Improved social behaviors, subjective feeling of trust, gazing behaviors at the eye region
Anagnostou et al. (2012) [24]	Intranasal (6 weeks)	No change in Diagnostic Analysis of Nonverbal Accuracy & Repetitive Behavior Scale Revised; improved performance in Reading-the-Mind-in-the-Eyes Test and quality of life
Domes et al. (2013) [26]	Intranasal (single dose)	Increased brain activity patterns in the right amygdala during face processing