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Effect of bafilomycin A1 on Ca2+ signals evoked by photolysis of caged NAADP in SKBR3 cells (A) Abolishment of Ca2+ signals evoked by photolysis of caged NAADP (100 nM) following bafilomycin A1 (1 μM) treatment. (B) The cumulative data from (A) plotted as % increase of the Ca2+ peak relative to baseline; mean data of 3–5 experiments; *, p < .05. Star indicates sequential flash uncagings.
