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Comparison of in vitro potency of (Rap) 2 -E1-(Rap) 2 vs. Rap(Q)-hRS7
|
Agents |
EC
50
(nM)
a
|
||||||
|---|---|---|---|---|---|---|---|
| MDA-MB-468 | MCF-7 | SKBR-3 | HCC1806 | BT-20 | MDA-MB-231 | HCC1395 | |
| (Rap)2-E1-(Rap)2 |
0.03 |
0.1 |
1.29 |
0.19 |
0.18 |
>50 |
~100 |
| Rap(Q)-hRS7 | 3.8b | >100b | >100b | 10.1 | >100 | NDc | NDc |
aHalf maximal effective concentration; bFrom previous results [34]; cNot determined.
