Table 2.
Echocardiographic structural data
| Parameters | SHR (n = 21) | SHR-DM (n = 16) | P value |
|---|---|---|---|
| HR (bpm) |
322 ± 40 |
287 ± 40 |
0.010 |
| LVDD (mm) |
8.56 ± 1.03 |
8.73 ± 0.77 |
0.572 |
| LVDD/BW (mm/kg) |
24.2 (22.1 – 26.0) |
31.2 (25.3 – 34.0) |
0.001 |
| LVDD/T (mm/cm) |
2.02 ± 0.24 |
2.09 ± 0.19 |
0.445 |
| LVSD (mm) |
4.71 ± 1.27 |
5.54 ± 1.19 |
0.043 |
| PWT (mm) |
1.83 (1.75 – 1.90) |
1.72 (1.66 – 1.79) |
0.031 |
| SWT (mm) |
1.86 (1.77 – 1.91) |
1.74 (1.66 – 1.83) |
0.023 |
| AO (mm) |
4.50 (4.45 – 4.85) |
4.45 (4.30 – 4.90) |
0.701 |
| LA (mm) |
7.46 ± 1.12 |
7.51 ± 1.27 |
0.900 |
| LA/BW (mm/kg) |
21.5 ± 3.72 |
26.3 ± 5.82 |
0.003 |
| LA/T (mm/cm) |
1.75 ± 0.22 |
1.82 ± 0.33 |
0.513 |
| LV mass (g) |
1.24 (1.05 – 1.39) |
1.18 (1.05 – 1.41) |
0.673 |
| LV mass/BW (g/Kg) |
3.35 (3.12 – 4.04) |
4.16 (3.27 – 5.05) |
0.088 |
| RWT |
0.44 ± 0.07 |
0.40 ± 0.05 |
0.046 |
| Tibia length (cm) | 4.15 (4.10-4.19) | 4.20 (4.10-4.20) | 0.213 |
Data are expressed as mean ± standard deviation or median and 25th and 75th percentile. SHR: spontaneously hypertensive rats without diabetes mellitus; SHR-DM: SHR with diabetes mellitus; BW: body weight; HR: heart rate; LVDD and LVSD: left ventricular (LV) diastolic and systolic diameter, respectively; PWT: LV posterior wall thickness; SWT: LV septal wall thickness; AO: aortic diameter; LA: left atrial diameter; LV mass: LV mass; RWT: relative wall thickness; T: tibia length. P value: result of statistical test (Student’s t or Mann-Whitney tests).