Table 3.
Echocardiographic left ventricular functional data
| Parameters | SHR (n = 21) | SHR-DM (n = 16) | P value |
|---|---|---|---|
| FS (%) |
45.8 ± 9.35 |
37.1 ± 8.94 |
0.005 |
| Ejection fraction |
0.83 ± 0.08 |
0.74 ± 0.11 |
0.005 |
| PWSV (mm/s) |
30.9 ± 7.10 |
26.4 ± 5.94 |
0.039 |
| E-wave (cm/s) |
77.1 ± 25.2 |
92.9 ± 30.4 |
0.090 |
| A-wave (cm/s) |
72.2 ± 37.1 |
34.4 ± 20.5 |
0.001 |
| E/A |
0.75 (0.62 – 4.37) |
1.41 (1.19 – 6.43) |
0.014 |
| EDT (ms) |
38.1 ± 5.67 |
33.2 ± 7.09 |
0.132 |
| IVRT (ms) | 36.9 ± 7.60 | 43.4 ± 6.44 | 0.008 |
Data are expressed as mean ± standard deviation or median and 25th and 75th percentile. SHR: spontaneously hypertensive rats without diabetes mellitus; SHR-DM: SHR with diabetes mellitus; FS: endocardial fractional shortening; PWSV: posterior wall shortening velocity; E: early diastolic mitral inflow velocity; A: late diastolic mitral inflow velocity; EDT: E-wave deceleration time; IVRT: isovolumetric relaxation time. P value: result of statistical test (Student’s t or Mann-Whitney tests).