Table 4.
Basal isolated papillary muscle data
| Parameters | SHR (n = 13) | SHR-DM (n = 12) | P value |
|---|---|---|---|
| DT (g/mm2) |
5.60 (2.57 – 7.99) |
3.05 (2.17 – 5.42) |
0.121 |
| RT (g/mm2) |
0.92 ± 0.37 |
0.81 ± 0.27 |
0.383 |
| TPT (ms) |
236 ± 30 |
264 ± 24 |
0.024 |
| +dT/dt (g/mm²/s) |
43.2 ± 22.5 |
25.7 ± 15.4 |
0.033 |
| -dT/dt (g/mm²/s) |
19.5 ± 9.54 |
15.3 ± 6.96 |
0.229 |
| CSA (mm2) | 1.04 ± 0.38 | 1.13 ± 0.30 | 0.511 |
Data are expressed as mean ± standard deviation or median and 25th and 75th percentile. SHR: spontaneously hypertensive rats without diabetes mellitus; SHR-DM: SHR with diabetes mellitus; DT: peak developed tension; RT: resting tension; TPT: time to peak tension; +dT/dt: maximum tension development rate; -dT/dt: maximum tension decline rate; CSA: papillary muscle cross sectional area. P value: result of statistical test (Student’s t or Mann-Whitney tests).