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Evaluation of oxidative stress
| Variables | SHR (n = 8) | SHR-DM (n = 8) | P value |
|---|---|---|---|
| Lipid hydroperoxide (nmol/ml) |
8.80 ± 0.84 |
11.1 ± 1.04 |
0.001 |
| Superoxide dismutase (U/mg) |
687 ± 84 |
396 ± 50 |
0.001 |
| Glutathione peroxidase (U/ml) | 20.7 ± 1.98 | 17.6 ± 1.95 | 0.008 |
Data are expressed as mean ± standard deviation. SHR: spontaneously hypertensive rats without diabetes mellitus; SHR-DM: SHR with diabetes mellitus. P value: result of statistical test (Student’s t test).
