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. 2014 May 1;34(5):394–403. doi: 10.1089/jir.2013.0062

FIG. 1.

FIG. 1.

The miscarriage-inducing effect of interferon-gamma (IFN-γ) in mice peri-implantation (D4–D7 of pregnancy). (A) Overall pregnancy uterine pictures and representative uterine implantation site sections. Trypan blue was administered by mouse tail vein injection to stain the implantation sites of the uterus on D5. The uterine implantation site sections were stained with hematoxylin. The letter e is for embryo and s is for uterine stroma. (B) Histogram of implantation site numbers in the uterus on D5–D7 with the administration of IFN-γ. All results are expressed in terms of the implantation site number in the uterus on different days of pregnancy. The bars represent the SD of the mean. The data at each point were derived from 9 separate samples from pregnant mice. A total of 54 samples from pregnant mice were observed to perform this count. *P<0.05, **P<0.01.