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. 2014 May 1;34(5):366–375. doi: 10.1089/jir.2013.0049

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Copyright 2014, Mary Ann Liebert, Inc.

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FIG. 4. — The dynamic change of NK cell functions during the course of treatment. Individual patients were treated with interferon and the frequency of NK and activated NK cells were characterized by flow cytometry analysis. PBMCs separated from patients were incubated with K562 cells, then marked CD107a and IFN-γ to determine the functions. (A) The correlation between CD107a⁺ NK cell and the level of serum ALT. (B) The correlation between IFN-γ⁺ NK cell and the level of serum ALT. (C) The dynamic change of CD107a⁺ NK cells. (D) The dynamic change of IFN-γ⁺ NK cells (*P<0.5; **P<0.01; ***P<0.001).