Table 2.
The laboratory data, sources of infection, sepsis status, admission site and initial inappropriate antibiotic use among the inhospital survivors and non-survivors
| Factors | Survivors (n = 118) | Non-survivors (n = 104) | OR | 95% CI | P value |
|---|---|---|---|---|---|
| WBC ( /uL) |
|
|
|
|
|
| <4000 |
8 (7.0%) |
6 (5.9%) |
0.828 |
0.277-2.473 |
0.95 |
| 4000-10000 |
42 (36.8%) |
16 (15.7%) |
0.319 |
0.166-0.614 |
<0.01 |
| 10000-20000 |
50 (43.9%) |
51 (50.0%) |
1.280 |
0.749-2.188 |
0.44 |
| >20000 |
14 (12.3%) |
29 (28.4%) |
2.838 |
1.401-5.746 |
<0.01 |
| Creatinine |
1.68 ± 1.35 |
2.56 ± 1.56 |
|
|
<0.01 |
| Albumin |
3.08 ± 0.53 |
2.84 ± 0.52 |
|
|
<0.01 |
| C-reactive protein |
10.10 ± 7.15 |
13.39 ± 7.92 |
|
|
0.03 |
| Thrombocytopenia |
6 (5.1%) |
5 (4.8%) |
0.943 |
0.279-3.184 |
1.00 |
| Pulmonary infection |
25 (21.2%) |
33 (31.7%) |
1.729 |
0.945-3.165 |
0.10 |
| UTI |
39 (33.1%) |
26 (25.0%) |
0.675 |
0.376-1.214 |
0.24 |
| IAI |
8 (6.8%) |
1 (1.0%) |
0.133 |
0.016-1.086 |
0.04 |
| SSTI |
8 (6.8%) |
9 (8.7%) |
1.303 |
0.483-3.510 |
0.79 |
| SWI |
0 |
0 |
|
|
|
| CRBSI |
14 (11.9%) |
14 (13.5%) |
1.156 |
0.523-2.553 |
0.88 |
| CNS infection |
0 |
0 |
|
|
|
| Unknown infection focus |
24 (20.3%) |
23 (22.1%) |
1.112 |
0.584-2.119 |
0.87 |
| Initial inappropriate antibiotic use |
59 (50.0%) |
72 (69.2%) |
2.250 |
1.297-3.904 |
<0.01 |
| Sepsis |
84 (71.2%) |
34 (32.7%) |
0.197 |
0.111-0.348 |
<0.01 |
| Severe Sepsis |
20 (16.9%) |
20 (19.2%) |
1.167 |
0.588-2.314 |
0.79 |
| Septic Shock |
9 (7.6%) |
44 (42.3%) |
8.881 |
4.06-19.44 |
<0.01 |
| MODS |
- |
5 (4.8%) |
- |
- |
0.02 |
| Confusion |
79 (66.9%) |
96 (92.3%) |
5.924 |
2.62-13.41 |
<0.01 |
| RR >30 (per minute) |
27 (22.9%) |
34 (32.7%) |
1.637 |
0.904-2.964 |
0.14 |
| BUN >20 (mg/dl) |
79 (66.9%) |
92 (88.5%) |
3.785 |
1.854-7.725 |
<0.01 |
| SBP <90 mmHg or DBP <60 mmHg |
17 (14.4%) |
52 (50.0%) |
5.941 |
3.13-11.29 |
<0.01 |
| Community - acquired |
24 (20.3%) |
12 (11.5%) |
0.511 |
0.241-1.082 |
0.11 |
| Nursing home – acquired |
42 (35.6%) |
15 (14.4%) |
0.305 |
0.157-0.593 |
<0.01 |
| Hospital – acquired |
53 (44.9%) |
76 (73.1%) |
3.329 |
1.892-5.857 |
<0.01 |
| ICU stay |
17 (14.4%) |
45 (43.3%) |
4.531 |
2.380-8.626 |
<0.01 |
| LOS > 30 days | 34 (28.8%) | 51 (49.0%) | 2.377 | 1.367-4.136 | <0.01 |
WBC White cell counts, UTI Urinary tract infection, IAI Intra-abdominal infection, SSTI Superficial soft infection, CRBSI Catheter related blood stream infection, CNS Central venous infection, CVC Central venous catheter, OP Operation, LOS Length of stay, MODS Multiple organ dysfunction syndrome, RR Respiratory rate, BUN Blood urea unit, SBP Systolic blood pressure, DBP Diastolic blood pressure. Except for two variables including LOS > 30 days and ICU stay (ICU care is required during hospitalization), all the variables were measured when bacteremia occurred.