Figure 2.

 Effects of acarbose on Membrane type‐1 matrix metalloproteinase (MT1‐MMP) expression and arterial stiffness. (a) Circulating peripheral blood mononuclear cells (PBMNC) from patients with type 2 diabetes mellitus were examined for the frequencies of CD14 positive cells expressing MT1‐MMP at the single cell level using flow cytometry. The expression of MT1‐MMP on PBMNC was significantly decreased by acarbose treatments. (b) Cardio‐ankle vascular index (CAVI) was measured as the arterial stiffness. Value of CAVI was significantly reduced after acarbose treatment (from 9.44 ± 0.36 to 8.98 ± 0.28; P = 0.031), although the changes were not significant in blood pressure and heart rate.