Table 2.  Changes of gelatinolytic activity and inflammatory cytokines data.

	Acarbose		P‐value
	Before	12 months later
MMP‐2, ng/mL (CV%)	837 ± 118 (11)	731 ± 89 (12)	0.024
TIMP‐2, ng/mL (CV%)	82 ± 11 (13)	85 ± 18 (21)	0.32
MMP‐9, ng/mL (CV%)	36.3 ± 8.1 (22)	28.1 ± 6.2 (22)	0.048
TIMP‐1, ng/mL (CV%)	133 ± 13 (10)	153 ± 37 (24)	0.16
hs‐CRP, mg/L (CV%)	2.21 ± 0.86 (39)	1.49 ± 0.64 (43)	0.042
Pentraxin‐3, ng/mL (CV%)	2.47 ± 0.31 (13)	1.90 ± 0.21 (11)	0.0013

hs‐CRP, high‐sensitivity C‐reactive protein; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of matrix metalloproteinase.