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Ex‐4 treatment resulted in a significant decrease in the ratio of C/EBP‐homologous protein (CHOP)‐positive β‐cells in Akita mice. (a) Representative mouse pancreata at 5 weeks‐of‐age stained with insulin (red), CHOP (green) and DAPI (blue). (b) The number of CHOP‐positive β‐cells normalized per insulin‐positive area was quantified as described in Materials and Methods. Each column represents mean ± SE. **P < 0.01.
