Antibody secreting cell (ASC) responses to Ogawa OSPc:BSA (OSP, O-specific polysaccharide), lipopolysaccharide (LPS), and CtxB in patients and vaccinees. Mean circulating antigen-specific immunoglobulin A (IgA), IgG, and IgM ASC responses to Ogawa OSP, LPS, and CtxB with standard error bars (Figure 3A–C, respectively). Asterisks indicate a statistically significant difference (P ≤ 0.05) from baseline (Day 0 or Day 2) and “#” indicates a statistically significant difference (P ≤ 0.05) between similar days in vaccinees and patients.