Table 4.
Average expression data of upregulated genes during EXP/STA2 comparison based on resultant FDR value from the RP analysis equal or less to 0.05 in compared growth phases during SA production cultures
| Gene | Locus | Protein name a | Cellular function GO b | Average expression |
|---|---|---|---|---|
|
ykfE |
b0220 |
(ivy) Protein: inhibitor of vertebrate C-type lysozyme |
Amino acid metabolism |
29.2978 |
|
cysK |
b2414 |
Enzyme: cysteine synthase A |
Amino acid metabolism |
83.0796 |
|
gcvH |
b2904 |
Polypeptide: glycine cleavage system H protein |
Amino acid metabolism |
30.4955 |
|
gcvP |
b2903 |
Enzyme: glycine decarboxylase |
Amino acid metabolism |
33.3045 |
|
gcvT |
b2905 |
Enzyme: aminomethyltransferase |
Amino acid metabolism |
38.3509 |
|
gdhA |
b1761 |
Enzyme: glutamate dehydrogenase |
Amino acid metabolism |
20.9785 |
|
glyA |
b2551 |
Enzyme: serine hydroxymethyltransferase |
Amino acid metabolism |
23.7380 |
|
tnaA |
_b3708 |
L-cysteine desulfhydrase/tryptophanase |
Amino acid metabolism |
139.6125 |
|
tnaL |
b3707 |
tna operon leader peptide |
Amino acid metabolism |
62.9786 |
|
ompT |
b0565 |
Enzyme: OM protease VII (OM protein 3b) |
Catalytic activity |
35.7201 |
|
fimC |
b4316 |
Polypeptide: periplasmic chaperone, required for type 1 fimbriae |
Cell envelope |
63.3469 |
|
fimD |
b4317 |
Polypeptide: OM protein; export and assembly of type 1 fimbriae |
Cell envelope |
25.6637 |
|
nlpA |
b3661 |
Polypeptide: lipoprotein-28 |
Cell envelope |
48.3194 |
|
ydiQ |
b1697 |
Polypeptide: putative subunit of YdiQ-YdiR flavoprotein |
Electron carrier activity |
29.9950 |
|
nrdA |
b2234 |
Protein: ribonucleoside diphosphate reductase 1, α subunit dimer |
Nucleotide/nucleoside metabolism |
37.6063 |
|
yciW |
b1287 |
Polypeptide: predicted oxidoreductasePolypeptide: predicted oxidoreductase |
Out of GOs |
116.1438 |
|
yieI |
b3716 |
(cbrB) Polypeptide: predicted IM protein |
Out of GOs |
31.9090 |
|
yeeN |
b1983 |
Polypeptide: conserved protein |
Regulatory |
22.0828 |
|
yhiE |
b3512 |
(gadE) Polypeptide: GadE DNA-binding transcriptional activator |
Regulatory |
46.2077 |
|
yhiW |
b3515 |
(gadW) Polypeptide: GadW DNA-binding transcriptional dual regulator |
Regulatory |
37.7545 |
|
hdeA |
b3510 |
Protein: HdeA dimer, inactive form of acid-resistance protein |
Stress response |
32.4174 |
|
hdeB |
b3509 |
Polypeptide: acid stress chaperone |
Stress response |
56.2185 |
|
b0023 |
b0023 |
Polypeptide: 30S ribosomal subunit protein S20 |
Structural molecule activity |
45.8728 |
|
cysC |
b2750 |
Enzyme: adenylylsulfate kinase |
Sulfur metabolism |
52.8463 |
|
cysD |
cysD |
Polypeptide: CysD |
Sulfur metabolism |
236.2573 |
|
cysH |
b2762 |
Enzyme: 3′-phospho-adenylylsulfate reductase |
Sulfur metabolism |
194.5029 |
|
cysJ |
b2764 |
Enzyme: sulfite reductase, flavoprotein subunit complex |
Sulfur metabolism |
62.3545 |
|
ydjN |
b1729 |
Polypeptide: predicted transporter |
Transport |
43.4944 |
|
dppB |
b3543 |
Polypeptide: dipeptide ABC transporter - putative membrane subunit |
Transport |
23.0830 |
|
dppF |
b3540 |
Polypeptide: dipeptide ABC transporter - putative ABC binding subunit |
Transport |
32.6107 |
|
fecA |
b4291 |
Polypeptide: ferric citrate OMP FecA |
Transport |
23.6130 |
|
malE |
b4034 |
Maltose ABC transporter - periplasmic binding protein |
Transport |
230.4651 |
|
ompC |
b2215 |
Transporter: OMP C |
Transport |
61.2832 |
|
oppB |
b1244 |
Polypeptide: murein tripeptide ABC transporter/peptide ABC transporter - putative membrane subunit |
Transport |
44.3550 |
|
proV |
b2677 |
Polypeptide: glycine betaine/proline ABC transporter - ATP binding subunit |
Transport |
34.7488 |
|
proW |
b2678 |
Polypeptide: glycine betaine/proline ABC transporter - membrane subunitPolypeptide: glycine betaine/proline ABC transporter - membrane subunit |
Transport |
35.6683 |
| proX | b2679 | Polypeptide: glycine betaine/proline ABC transporter - periplasmic binding protein | Transport | 48.2957 |
aRetrieved from EcoCyc database, bBiological functions were assigned according to the EcoCyc database for E. coli strain MG1655 and broadly grouped on the basis of GO terms [17].