Table 2.
IDH study summary data: summary of the analysis of 19 IDH patients
| Total enrolled |
n = 60* |
|
|
| HTLV-1 + |
n = 33 |
|
|
| IDH confirmed |
n = 19 |
|
|
| HTLV-1/HIV + |
n = 9 |
|
|
| (of n = 33) | |||
| Ethnicity |
all black african |
|
|
| HTLV-1 subtype |
Cosmopolitan (1a) |
|
|
| Age |
mean |
8 years |
|
| |
range |
8 months −15 years (IQR 7–11) |
|
| Gender distribution |
male |
68.40% |
|
| |
female |
52.60% |
|
| Microbiology |
Staph Aureus |
55.60% |
|
| |
Streptococcal spp |
33.60% |
|
| Clinical examination |
|
dermatological |
scalp (78.9%) and axilla (73.7%) commonest sites of involvement |
| |
|
neurological |
no evidence for HAM/TSP |
| |
|
opthalmological |
corneal opacities 3(15.6%) |
| Immunologic parameters |
|
mean (normals) g/l |
|
| |
IgA |
3.52 (0.65-2.9) |
|
| |
IgG |
22.6 (5.2-15.6) |
|
| |
IgM |
1.38 (0.28-2.4) |
|
| SPEP |
|
mean (normals) g/l |
|
| |
Albumin |
32.5 (32–50) |
|
| |
Alpha 1 globulin |
4.0 (1.72-3.30) |
|
| |
Alpha 2 globulin |
11.1 (4.2-8.7) |
|
| |
Beta globulin |
11.4 (5.2-10.5) |
|
| |
Gamma globulin |
26.7 (7.1-14.5) |
|
| Blood counts |
|
mean (normals) |
|
| |
Hb |
12.3 (11.5-13.5) g/dl |
|
| |
WBCC |
10.1 (4-11x10^9) |
|
| |
Platelets |
405 (150-450x10^9) |
|
| |
ESR |
40 (3–9 mm/hr) |
|
| |
CD4 count |
1958 (500–1500) cells/mm3 |
|
| |
CD8 count |
1150 (436–2278) cells/mm3 |
|
| |
CD4 : CD8 ratio |
1.7:1 |
|
| HTLV-1 proviral load |
|
mean (range%) |
|
| 10.5 (1.8-29.8) |
*remaining patients (n = 27) not further analysed, majority of which had HIV related seborrhoiec dermatitis.