Table 4.
Different gene significant upregulated GO
| GO item | Fold enrichment | P value |
|---|---|---|
| Germ cell programmed cell death |
32.29 |
2.80 × 10-3 |
| Developmental programmed cell death |
19.37 |
8.95 × 10-3 |
| Protein retention in ER lumen |
13.84 |
1.80 × 10-2 |
| Germ cell migration |
13.45 |
3.65 × 10-4 |
| Melanocyte differentiation |
9.22 |
8.27 × 10-3 |
| Mitotic cell cycle spindle assembly checkpoint |
8.81 |
4.36 × 10-2 |
| Negative regulation of mitotic metaphase/anaphase transition |
8.81 |
4.36 × 10-2 |
| Pigmentation during development |
8.69 |
1.14 × 10-4 |
| Pigment cell differentiation |
8.61 |
1.01 × 10-2 |
| Antigen processing and presentation of peptide antigen via MHC class I |
7.60 |
1.44 × 10-2 |
| Positive regulation of calcium ion transport into cytosol |
6.46 |
2.26 × 10-2 |
| Regulation of calcium ion transport into cytosol |
5.57 |
1.16 × 10-2 |
| T cell proliferation |
4.78 |
4.95 × 10-2 |
| Regulation of transforming growth factor beta receptor signaling pathway |
4.14 |
3.15 × 10-2 |
| Positive regulation of homeostatic process |
4.04 |
3.42 × 10-2 |
| Response to vitamin A |
3.84 |
4.00 × 10-2 |
| Pigmentation |
3.83 |
9.50 × 10-3 |
| Mitotic cell cycle checkpoint |
3.75 |
4.30 × 10-2 |
| Regulation of calcium ion transport |
3.74 |
5.31 × 10-3 |
| Extracellular matrix organization |
3.73 |
3.63 × 10-4 |
| Alcohol biosynthetic process |
3.67 |
4.62 × 10-2 |
| Regulation of metal ion transport |
3.59 |
3.49 × 10-3 |
| Leukocyte mediated immunity |
3.38 |
5.04 × 10-3 |
| Cellular response to insulin stimulus |
3.32 |
1.83 × 10-2 |
| Regulation of ion transport |
3.26 |
3.51 × 10-3 |
| Lymphocyte mediated immunity |
3.23 |
2.09 × 10-2 |
| Response to organic cyclic substance |
3.20 |
1.30 × 10-3 |
| Response to toxin |
3.18 |
3.98 × 10-2 |
| Double-strand break repair |
3.12 |
4.23 × 10-2 |
| Sphingolipid metabolic process |
3.01 |
2.82 × 10-2 |
| Response to molecule of bacterial origin |
3.00 |
1.70 × 10-2 |
| Adaptive immune response |
2.94 |
3.16 × 10-2 |
| Response to lipopolysaccharide |
2.94 |
3.16 × 10-2 |
| Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
2.94 |
3.16 × 10-2 |
| Cellular response to hormone stimulus |
2.91 |
2.77 × 10-3 |
| Response to insulin stimulus |
2.91 |
1.22 × 10-2 |
| Membrane lipid metabolic process |
2.79 |
3.91 × 10-2 |
| Activation of MAPK activity |
2.76 |
4.11 × 10-2 |
| Immune effector process |
2.65 |
8.66 × 10-3 |
| Protein processing |
2.59 |
2.27 × 10-2 |
| Extracellular structure organization |
2.57 |
4.72 × 10-3 |
| Response to oxidative stress |
2.56 |
4.95 × 10-3 |
| Positive regulation of MAP kinase activity |
2.53 |
3.86 × 10-2 |
| Regulation of MAP kinase activity |
2.52 |
1.21 × 102 |
| Amine transport |
2.46 |
2.99 × 10-2 |
| Camera-type eye development |
2.41 |
4.79 × 10-2 |
| Carbohydrate biosynthetic process |
2.41 |
4.79 × 10-2 |
| Protein oligomerization |
2.41 |
7.85 × 10-3 |
| Protein maturation |
2.38 |
3.54 × 10-2 |
| Nucleotide biosynthetic process |
2.26 |
1.29 × 102 |
| Nucleobase, nucleoside and nucleotide biosynthetic process |
2.17 |
1.69 × 10-2 |
| Nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process |
2.17 |
1.69 × 10-2 |
| Cell proliferation |
2.15 |
2.12 × 10-4 |
| Muscle organ development |
2.14 |
1.41 × 102 |
| Regulation of neurogenesis |
2.14 |
3.34 × 10-2 |
| Skeletal system development |
2.13 |
2.21 × 10-3 |
| Response to peptide hormone stimulus |
2.10 |
4.96 × 10-2 |
| Transmembrane receptor protein tyrosine kinase signaling pathway |
2.02 |
2.20 × 10-2 |
| Regulation of nervous system development |
2.02 |
3.63 × 10-2 |
| Nitrogen compound biosynthetic process |
1.99 |
5.98 × 10-3 |
| Enzyme linked receptor protein signaling pathway |
1.98 |
4.86 × 10-3 |
| Response to drug |
1.94 |
3.62 × 10-2 |
| Blood vessel development |
1.84 |
4.11 × 10-2 |
| Response to DNA damage stimulus |
1.82 |
1.20 × 10-2 |
| Induction of apoptosis |
1.82 |
2.14 × 10-2 |
| Induction of programmed cell death |
1.81 |
2.19 × 10-2 |
| Positive regulation of apoptosis |
1.80 |
7.74 × 10-3 |
| Vasculature development |
1.80 |
4.83 × 10-2 |
| Positive regulation of programmed cell death |
1.79 |
8.09 × 10-3 |
| Positive regulation of cell death |
1.78 |
8.74 × 10-3 |
| M phase |
1.77 |
2.70 × 10-2 |
| Response to hormone stimulus |
1.76 |
1.98 × 10-2 |
| Response to endogenous stimulus |
1.75 |
1.46 × 10-2 |
| Cell cycle phase |
1.72 |
1.82 × 10-2 |
| Response to abiotic stimulus |
1.67 |
3.73 × 10-2 |
| Protein kinase cascade |
1.66 |
3.89 × 10-2 |
| Cellular response to stress |
1.65 |
9.67 × 10-3 |
| Response to organic substance |
1.61 |
5.45 × 10-3 |
| Phosphorylation |
1.57 |
5.41 × 10-3 |
| Oxidation reduction |
1.57 |
1.51 × 10-2 |
| Phosphate metabolic process |
1.56 |
2.49 × 10-3 |
| Phosphorus metabolic process |
1.56 |
2.49 × 10-3 |
| Cell cycle process |
1.54 |
2.79 × 10-2 |
| Protein amino acid phosphorylation |
1.50 |
2.49 × 10-2 |
| Immune response |
1.50 |
2.35 × 10-2 |
| Regulation of cell proliferation |
1.44 |
3.02 × 10-2 |
| Regulation of programmed cell death |
1.43 |
2.88 × 10-2 |
| Regulation of cell death |
1.43 |
3.01 × 10-2 |
| Regulation of apoptosis | 1.41 | 3.91 × 10-2 |