Table 1.
C (BSA), mg/mL | C (BSA)/C (CPT), mg/mg | % BSA bound to the core | Hydrodynamic diametera, nm |
---|---|---|---|
Coated with (Hep/PLB16-5) shell, pH 3.0 | |||
0.35 | 0.62 | 97 ± 3 | 254 ± 15 |
0.64 | 1.16 | 91 ± 3 | 167 ± 12 |
1.28 | 1.01 | 43 ± 2 | 180 ± 15 |
1.90 | 1.13 | 30 ± 2 | 303 ± 14 |
2.50 | 4.96 | 100 ± 3 | 1152 ± 56 |
Coated with a (Hep/PLB16-5)4.5 shell, pH 7.4 | |||
0.24 | 0.24 | 64 ± 2 | 245 ± 2 |
0.36 | 0.36 | 69 ± 3 | 220 ± 4 |
0.64 | 0.69 | 54 ± 2 | 178 ± 2 |
CPVP = 1.44 mg/mL