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. Author manuscript; available in PMC: 2015 Apr 25.
Published in final edited form as: Int J Pharm. 2014 Feb 6;465(0):218–227. doi: 10.1016/j.ijpharm.2014.01.041

Table 1.

Amount of BSA-FITC bound to CPT cores at different concentration of protein.

C (BSA), mg/mL C (BSA)/C (CPT), mg/mg % BSA bound to the core Hydrodynamic diametera, nm
Coated with (Hep/PLB16-5) shell, pH 3.0
0.35 0.62 97 ± 3 254 ± 15
0.64 1.16 91 ± 3 167 ± 12
1.28 1.01 43 ± 2 180 ± 15
1.90 1.13 30 ± 2 303 ± 14
2.50 4.96 100 ± 3 1152 ± 56
Coated with a (Hep/PLB16-5)4.5 shell, pH 7.4
0.24 0.24 64 ± 2 245 ± 2
0.36 0.36 69 ± 3 220 ± 4
0.64 0.69 54 ± 2 178 ± 2
a

CPVP = 1.44 mg/mL