Table 2.

Association of the combined expression of Cav-1 and pERK with conventional histological parameters in RCC

	Cav-1 (n = 165)		p-ERK1/2 (n = 164)		Cav-1/pERK1/2 (n = 158)
	-	+	-	+	All other Tumours	+/+
Grade 1 & 2	69	47	75	43	93	19
Grade 3 & 4	25	24	29	17	36	10
		P = 0.390		P = 0.951		P = 0.091
Tumour size <7 cm	49	29	55	24	64	10
>7 cm	45	42	49	36	65	19
		P = 0.151		P = 0.112		P = 0.142
Vascular Invasion (-ve)	66	33	71	30	85	10
(+ve)	28	38	33	30	44	19
		P = 0.002*		P = 0.021*		P = 0.002*
Capsular Invasion (-ve)	83	55	90	47	109	22
(+ve)	11	16	14	13	20	7
		P = 0.063		P = 0.172		P = 0.267
Tumour Stage 1	44	21	50	17	55	7
Stage 2	31	14	28	15	38	4
Stage 3 & 4	19	36	26	28	36	18
		P = 0.0001*		P = 0.011*		P = 0.002*
Non- papillary	76	67	84	58	109	28
Papillary	18	4	20	2	20	1
		P = 0.011*		P = 0.004*		P = 0.084

* Indicates that statistical significance achieved to at least P < 0.05 with actual P value indicated in the Table itself.