Table 3.
Multivariate Cox regression hazard model for time to recurrence using a forward conditional selection method
| Prognostic indices model (n) | HR | 95% CI | P value |
|---|---|---|---|
| Grade 1 and 2 |
1 |
|
|
| Grade 3 and 4 |
3.4 |
1.9-6.1 |
<0.001* |
| No capsular invasion present |
1 |
|
|
| Capsular invasion present |
5.4 |
3.0-10.0 |
<0.001* |
| Cav-1 and p-ERK1/2 covariate negative |
1 |
|
|
| Cav-1 and p-ERK1/2 covariate positive | 4.2 | 2.3-7.5 | <0.001* |
Covariates used include: tumour grade, stage, size, capsular invasion, vascular invasion, Cav-1 and p-ERK1/2. The covariates of size, stage and vascular invasion are rejected as not influential in the model by the selection method.
CI = 95% confidence limit, HR = Hazard Ratio *denotes significance P < 0.001.