Table 4.
Concordance of Cav-1 and pERK expression in matched primary and secondary metastatic tumours
| Primary | Metastatic | Concordance | |||||
|---|---|---|---|---|---|---|---|
| Biomarker |
Cav (-) |
Cav (+) |
pERK (-) |
pERK (+) |
Concordant / Total |
Kappa |
P |
| Cav (-) |
3 |
0 |
|
14/16 |
0.67 |
P = 0.004 |
|
| Cav (+) |
2 |
11 |
|||||
| pERK (-) |
|
1 |
0 |
15/16 |
0.64 |
P = 0.006 |
|
| pERK (+) |
1 |
14 |
|||||
| |
Cav(-) pERK(-) |
Cav(+) pERK(-) |
Cav(-) pERK(+) |
Cav(+) pERK(+) |
|
|
|
| Cav(-)/pERK(-) |
0 |
0 |
0 |
0 |
14/16 | 0.74 | P < 0.001 |
| Cav(+)/pERK(-) |
0 |
1 |
0 |
0 |
|||
| Cav(-)/pERK(+) |
0 |
0 |
3 |
0 |
|||
| Cav(+)/pERK(+) | 1 | 0 | 1 | 10 | |||