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TF regulatory interaction network in OHT cells. We proposed the SIS as a measure for comparing the significance of the interaction between two TFs and constructed the TF regulatory interaction network based on the SIS scores between TFs in OHT cell line. The nodes represent regulatory TFs involved in interactions, and the edges represent significant interactions between TFs. Hub-TFs in OHT cells included C/EBP and Oct-1, in addition to E2F and E2F-1.
