Table 3.
Focal cortical grey matter volumes in children with PWS and healthy controls
|
PWS |
Control |
P
value between groups |
P
corr
value DEL versus control |
P
corr
value mUPD versus control |
P
corr
value mUPD versus DEL |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
|
DEL |
mUPD |
|
|
|
||||||
| Mean | SD | Mean | SD | Mean | SD | |||||
| Left entorhinal |
0.00153 |
0.00025 |
0.00123 |
0.00039 |
0.00148 |
0.00033 |
0.028 |
ns |
0.127 |
0.031 |
| Left banks of STS |
0.00237 |
0.00027 |
0.00217 |
0.00053 |
0.00204 |
0.00032 |
0.041 |
0.06 |
ns |
0.142 |
| Right superior parietal |
0.01359 |
0.00127 |
0.01363 |
0.00142 |
0.01163 |
0.00099 |
0.002 |
0.006 |
0.006 |
ns |
| Right lingual |
0.00621 |
0.00072 |
0.00532 |
0.00087 |
0.00584 |
0.00059 |
0.032 |
ns |
ns |
0.027 |
| Right parahippocampal |
0.00162 |
0.00021 |
0.00154 |
0.0003 |
0.00194 |
0.00036 |
0.014 |
0.11 |
0.016 |
ns |
| Right banks of STS | 0.00201 | 0.00026 | 0.00237 | 0.00033 | 0.00202 | 0.00045 | 0.032 | ns | 0.045 | 0.091 |
All measures presented in table are corrected for TIV. Pcorr values that did not survive the Bonferroni correction are included. DEL, deletion; mUPD, maternal uniparental disomy; ns, not significant; PWS, Prader–Willi syndrome; SD, standard deviation; STS, superior temporal sulcus; TIV, total intracranial volume.