. 2013 Oct 19;12:147. doi: 10.1186/1476-511X-12-147

Table 4.

Hepatic fatty acid composition in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

Fatty acid ( *% of total* )	Lean				Obese				Main effects
	CON	FLAX	FISH	SDA	CON	FLAX	FISH	SDA	Genotype	Diet	Interaction
LA^[18:2(n-6)]	1.19 ± 1.41	n.d.	n.d.	2.07 ± 1.42	0.86 ± 1.51	0.55 ± 1.19	0.99 ± 1.42	2.08 ± 1.49	P = 0.71	P = 0.25	P = 0.84
ALA^[18:3(n-3)]	0.21 ± 0.17^a	3.08 ± 0.17^d	0.93 ± 0.18^b	3.26 ± 0.17^d	0.43 ± 0.18^ab	1.78 ± 0.14^c	0.63 ± 0.17^ab	1.88 ± 0.18^c	P = 0.0016^†	P < 0.0001ⁱ	^ΔP < 0.0001
SDA^[18:4(n-3)]	n.d.	0.018 ± 0.26	0.81 ± 0.27	1.07 ± 0.25	0.15 ± 0.27	0.14 ± 0.21	0.19 ± 0.25	0.58 ± 0.26	P = 0.51	P = 0.0011ⁱⁱ	P = 0.17
AA^[20:4(n-6)]	14.09 ± 0.83^c	11.41 ± 0.85^b	3.58 ± 0.89^a	11.03 ± 0.83^b	5.53 ± 0.89^a	4.86 ± 0.70^a	4.24 ± 0.83^a	5.97 ± 0.88^a	P < 0.0001^†	P < 0.0001ⁱⁱⁱ	^ΔP < 0.0001
EPA^[20:5(n-3)]	n.d.	0.50 ± 0.61^a	6.20 ± 0.63^c	4.94 ± 0.60^c	0.63 ± 0.63^a	0.79 ± 0.50^a	2.37 ± 0.60^b	2.67 ± 0.63^b	P = 0.12	P < 0.0001ⁱⁱ	^ΔP < 0.0001
DPA^[22:5(n-3)]	0.12 ± 0.22^a	1.33 ± 0.23^bc	3.36 ± 0.24^d	3.94 ± 0.22^e	0.42 ± 0.24^ab	0.77 ± 0.19^b	1.70 ± 0.22^c	1.88 ± 0.24^c	P = 0.0006^†	P < 0.0001^iv	^ΔP < 0.0001
DHA^[22:6(n-3)]	2.26 ± 0.39^ab	4.49 ± 0.40^cd	10.11 ± 0.42^e	3.28 ± 0.39^bf	1.87 ± 0.42^a	2.43 ± 0.33^ab	5.63 ± 0.39^d	3.36 ± 0.41^bc	P = 0.0007^†	P < 0.0001^v	^ΔP < 0.0001
∑SFA	36.48 ± 1.55^c	36.12 ± 1.59^c	27.83 ± 1.66^a	32.41 ± 1.56^b	38.85 ± 1.66^d	41.14 ± 1.30^d	39.88 ± 1.56^d	39.43 ± 1.64^d	P = 0.0010^‡	P = 0.0055^vi	^ΔP = 0.0079
∑MUFA	41.99 ± 1.90	38.02 ± 1.85	33.93 ± 1.94	31.47 ± 1.82	46.57 ± 1.92	44.30 ± 1.51	39.91 ± 1.80	38.08 ± 1.90	P = 0.032^†	P = 0.0084^vi	P = 0.90
∑n3PUFA	1.92 ± 1.26^a	9.38 ± 1.29^b	21.82 ± 1.35^d	16.88 ± 1.27^c	3.65 ± 1.35^a	6.02 ± 1.06^e	10.76 ± 1.27^b	10.94 ± 1.33^b	P = 0.048^†	P < 0.0001^iv	^ΔP = 0.0057
∑n6PUFA	15.28 ± 1.70^a	10.6 ± 1.74^bc	3.04 ± 1.82^d	13.1 ± 1.71^ab	6.39 ± 1.82^de	5.41 ± 1.43^de	5.23 ± 1.71^de	8.05 ± 1.80^ce	P = 0.0040^†	P < 0.0001ⁱⁱⁱ	^ΔP < 0.0001

^ΔDifferent letters represent significance among means as determined by Bonferroni correction (P < 0.05).

Genotype Effect: ^†Lean > Obese; ^‡Obese > Lean.

Diet Effect: ⁱSDA, FLAX > FISH, CON; ⁱⁱSDA, FISH > FLAX, CON; ⁱⁱⁱCON > SDA, FLAX > FISH; ^ivFISH > SDA > FLAX > CON; ^vFISH > SDA, FLAX > CON; ^viCON, FLAX > FISH, SDA.

n.d.- not detectable.