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. 2013 Oct 19;12:147. doi: 10.1186/1476-511X-12-147

Table 6.

Epidydimal adipose tissue fatty acid profile in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

Fatty acid ( % of total )
 Lean
 Obese
 Main effect
  
  CON FLAX FISH SDA CON FLAX FISH SDA Genotype Diet Interaction
LA [18:2(n-6)]
1.12 ± 0.18
 0.87 ± 0.18
 0.81 ± 0.18
 0.67 ± 0.18
 1.33 ± 0.19
 1.10 ± 0.17
 1.32 ± 0.20
 0.86 ± 0.20
 P = 0.25
 P = 0.025i
 P = 0.69
ALA [18:3(n-3)]
1.14 ± 0.10ab
 7.88 ± 0.11c
 1.94 ± 0.10e
 7.47 ± 0.11d
 0.79 ± 0.11b
 5.14 ± 0.10f
 1.17 ± 0.12a
 4.71 ± 0.12g
 P < 0.0001†
 P < 0.0001ii
 ΔP < 0.0001
SDA [18:4(n-3)]
0.05 ± 0.074a
 0.04 ± 0.08a
 0.28 ± 0.073c
 5.06 ± 0.075b
 0.004 ± 0.08a
 0.005 ± 0.07a
 0.14 ± 0.082a
 2.51 ± 0.082d
 P < 0.0001†
 P < 0.0001iii
 ΔP < 0.0001
AA [20:4(n-6)]
0.43 ± 0.03
 0.27 ± 0.035
 0.35 ± 0.034
 0.43 ± 0.04
 0.56 ± 0.037
 0.32 ± 0.032
 0.34 ± 0.038
 0.45 ± 0.04
 P = 0.36
 P < 0.0001iv
 P = 0.15
EPA [20:5(n-3)]
0.14 ± 0.09
 0.15 ± 0.087
 1.21 ± 0.086
 0.59 ± 0.089
 n.d.
 0.07 ± 0.08
 0.88 ± 0.10
 0.51 ± 0.10
 P = 0.16
 P < 0.0001v
 P = 0.30
DPA [22:5(n-3)]
0.12 ± 0.07ad
 0.24 ± 0.076ad
 0.89 ± 0.073c
 0.61 ± 0.076b
 0.04 ± 0.08a
 0.28 ± 0.070d
 1.05 ± 0.083c
 1.00 ± 0.082c
 P = 0.20
 P < 0.0001vi
 ΔP = 0.0029
DHA [22:6(n-3)]
0.11 ± 0.10
 0.18 ± 0.10
 1.69 ± 0.10
 0.22 ± 0.10
 0.11 ± 0.10
 0.33 ± 0.088
 1.45 ± 0.10
 0.53 ± 0.10
 P = 0.82
 P < 0.0001v
 P = 0.52
∑SFA
 22.68 ± 0.44a
 23.06 ± 0.44a
 25.66 ± 0.43c
 20.59 ± 0.44b
 27.91 ± 0.47d
 27.84 ± 0.41d
 30.43 ± 0.49e
 27.66 ± 0.48d
 P < 0.0001‡
 P < 0.0001vii
 ΔP < 0.0001
∑MUFA
 69.12 ± 0.50a
 62.27 ± 0.51b
 56.64 ± 0.50d
 53.59 ± 0.51c
 61.64 ± 0.54b
 56.39 ± 0.48d
 51.00 ± 0.56e
 50.55 ± 0.56e
 P < 0.0001†
 P < 0.0001viii
 ΔP = 0.0055
∑n3PUFA
 1.65 ± 0.36a
 8.61 ± 0.37d
 6.08 ± 0.35c
 14.65 ± 0.37f
 0.83 ± 0.39a
 5.78 ± 0.34c
 4.76 ± 0.40b
 9.92 ± 0.40e
 P < 0.0001†
 P < 0.0001ix
 ΔP < 0.0001
∑n6PUFA 1.55 ± 0.17 1.15 ± 0.17 1.16 ± 0.17 1.12 ± 0.18 1.88 ± 0.18 1.42 ± 0.16 1.66 ± 0.19 1.31 ± 0.19 P = 0.17 P = 0.0046x P = 0.76

ΔDifferent letters represent significance among means as determined by Bonferroni correction (P < 0.05).

Genotype Effect: †Lean > Obese; ‡Obese > Lean.

Diet Effect: iCON, FISH, FLAX > SDA; iiFLAX > SDA > FISH > CON; iiiSDA > FISH > CON, FLAX; ivCON > SDA > FISH, FLAX; vFISH > SDA > FLAX, CON; viFISH > SDA > FLAX > CON; viiFISH > FLAX, CON > SDA; viiiCON > FLAX > FISH > SDA; ixSDA > FLAX > FISH > CON; xCON > FISH, FLAX, SDA.

n.d.- not detectable.