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. 2013 Oct 19;12:147. doi: 10.1186/1476-511X-12-147

Table 8.

Soleus muscle fatty acid profile in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

Fatty acid ( % of total )
 Lean
 Obese
 Main effect
  
  CON FLAX FISH SDA CON FLAX FISH SDA Genotype Diet Interaction
LA [18:2(n-6)]
0.06 ± 0.02ac
 0.007 ± 0.02b
 0.02 ± 0.02abc
 0.04 ± 0.02abc
 0.03 ± 0.01ab
 0.02 ± 0.01ab
 0.03 ± 0.02ab
 0.07 ± 0.01c
 P = 0.95
 P = 0.0045i
 P = 0.64
ALA [18:3(n-3)]
1.71 ± 0.64
 4.79 ± 0.69
 1.88 ± 0.67
 4.08 ± 0.65
 1.80 ± 0.69
 3.51 ± 0.54
 1.32 ± 0.66
 1.80 ± 0.67
 P = 0.23
 P < 0.0001ii
 P = 0.18
SDA [18:4(n-3)]
0.66 ± 0.35
 0.39 ± 0.38
 0.47 ± 0.38
 2.72 ± 0.36
 0.044 ± 0.38
 0.15 ± 0.30
 0.19 ± 0.37
 0.41 ± 0.37
 P = 0.067†
 P < 0.0001i
 ΔP = 0.0020
AA [20:4(n-6)]
5.37 ± 0.64b
 3.40 ± 0.70a
 1.90 ± 0.68a
 3.58 ± 0.65a
 3.60 ± 0.70ab
 2.90 ± 0.54a
 3.74 ± 0.67ab
 3.63 ± 0.67ab
 P = 0.91
 P = 0.026iii
 ΔP = 0.019
EPA [20:5(n-3)]
0.41 ± 0.21
 0.48 ± 0.22
 1.66 ± 0.22
 1.41 ± 0.21
 0.32 ± 0.22
 0.22 ± 0.17
 0.85 ± 0.21
 1.11 ± 0.21
 P = 0.15
 P < 0.0001iv
 P = 0.18
DPA [22:5(n-3)]
1.19 ± 0.33
 1.71 ± 0.36
 1.69 ± 0.35
 2.87 ± 0.34
 0.99 ± 0.36
 0.95 ± 0.28
 1.51 ± 0.34
 2.15 ± 0.35
 P = 0.28
 P < 0.0001i
 P = 0.58
DHA [22:6(n-3)]
4.14 ± 1.00ac
 4.82 ± 1.08ab
 7.09 ± 1.06b
 4.06 ± 1.01a
 2.27 ± 1.08a
 1.87 ± 0.84a
 3.57 ± 1.03ac
 5.01 ± 1.04c
 P = 0.16
 P = 0.054iv
 ΔP = 0.043
∑SFA
 29.69 ± 0.64
 29.50 ± 0.70
 31.17 ± 0.68
 28.54 ± 0.65
 30.12 ± 0.70
 30.15 ± 0.54
 32.38 ± 0.67
 30.24 ± 0.68
 P = 0.24
 P = 0.0004v
 P = 0.65
∑MUFA
 50.76 ± 2.26
 51.57 ± 2.45
 46.00 ± 2.39
 46.86 ± 2.29
 56.05 ± 2.45
 50.83 ± 1.90
 47.21 ± 2.34
 42.56 ± 2.36
 P = 0.90
 P < 0.0001vi
 P = 0.093
∑n3PUFA
 8.32 ± 1.52
 12.29 ± 1.65
 13.00 ± 1.61
 15.63 ± 1.54
 5.54 ± 1.65
 6.79 ± 1.28
 7.67 ± 1.57
 10.88 ± 1.59
 P = 0.023†
 P < 0.0001vii
 P = 0.72
∑n6PUFA 5.41 ± 0.65c 3.41 ± 0.70b 1.92 ± 0.69a 3.62 ± 0.66b 3.62 ± 0.70b 2.91 ± 0.55ab 3.76 ± 0.67b 3.68 ± 0.68b P = 0.91 P = 0.026iii ΔP = 0.020

ΔDifferent letters represent significance among means as determined by Bonferroni correction (P < 0.05).

Genotype Effect: †Lean > Obese; Obese > Lean.

Diet Effect: iSDA > CON, FISH > FLAX; iiFLAX > SDA > FISH, CON; iiiCON > SDA, FLAX, FISH; ivSDA, FISH > FLAX, CON; vFISH > CON, FLAX, SDA; viCON, FLAX > FISH, SDA; viiSDA > FISH, FLAX > CON.