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. 2014 Jan 10;15(Suppl 1):S14. doi: 10.1186/1471-2105-15-S1-S14

Figure 1.

Figure 1

Simplified schema of the bone/cartilage tissue engineering approach. Cells extracted from a donor tissue are expanded and seeded in a biomaterial. Tissue growth (and cell differentiation, if starting from stem cells) can be evaluated either in vitro or in vivo. In the latter case, implant can be in ectopic or orthotopic mode, depending on the size of the model organism and the necessity to evaluate the biomechanical stress on the tissue.