Table 2.
Genes significantly changed in the control challenge compared to baseline
| ||||||||
---|---|---|---|---|---|---|---|---|
# | Name | Symbol | GeneID | 0vs2 h | 0vs6 h | p | ||
1 |
ABCA1 |
ABCA1 |
19 |
1,33 |
1,40 |
0.001 |
||
2 |
FLaP |
ALOX5AP |
241 |
1,38 |
1,12 |
0.023 |
||
3 |
CXCR2 = IL-8RB |
CXCR2 |
3579 |
1,26 |
1,09 |
0.042 |
||
4 |
IL1RA |
IL1RN |
3557 |
1,19 |
1,17 |
0.009 |
||
5 |
NLRP3 |
NLRP3 |
114548 |
1,12 |
1,08 |
0.011 |
||
6 |
PPARG |
PPARG |
5468 |
-1,33 |
-1,11 |
0.004 |
||
7 |
PTX3 |
PTX3 |
5806 |
-1,37 |
-1,50 |
0.013 |
||
8 |
TLR2 (LPS) |
TLR2 |
7097 |
-1,13 |
-1,21 |
0.030 |
||
9 |
TNF-α |
TNF |
7124 |
1,18 |
1,18 |
0.025 |
||
10 |
CCR6 |
CCR6 |
1235 |
1,02 |
1,23 |
0.017 |
||
11 |
DUSP2 |
DUSP2 |
1844 |
-1,64 |
-1,55 |
0.006 |
||
12 |
FPR2/ALX |
FFRA1 |
2358 |
1,05 |
-1,02 |
0.041 |
||
13 |
ERK |
MAPK1 |
5594 |
1,11 |
1,05 |
0.022 |
||
Genes significantly changed in OGTT compared to control challenge
| ||||||||
# |
Name |
Symbol |
GeneId |
p |
OGTT |
Control |
||
0vs2 h |
0vs6 h |
0vs2 h |
0vs6 h |
|||||
1 |
CXCR3 |
CXCR3 |
2833 |
0.009 |
1,11 |
-1,07 |
-1,04 |
1,23 |
2 |
IL10RA |
IL10RA |
3587 |
0.016 |
-1,14 |
-1,26 |
-1,12 |
-1,06 |
3 |
INSIG1 (insulin induced gene 1) |
INSIG1 |
3638 |
0.031 |
-1,02 |
-1,06 |
-1,04 |
1,01 |
4 |
pyruvate dehydrogenase kinase 4 |
PDK4 |
5166 |
0.009 |
-3,11 |
1,66 |
1,11 |
1,37 |
5 |
ITGB1 |
ITGB1 |
3688 |
0.047 |
-1,09 |
-1,10 |
-1,06 |
1,09 |
6 |
lipocalin-2 |
LCN2 |
3934 |
0.0002 |
-1,07 |
-1,29 |
1,10 |
1,03 |
7 |
carnitine-acylcarnitine translocase |
SLC25A20 |
788 |
0.031 |
-1.31 |
1,26 |
1,08 |
1,11 |
Genes significantly changed in OLTT compared to control challenge
| ||||||||
# |
Name |
Symbol |
GeneId |
p |
OLTT |
Control |
||
0vs2 h |
0vs6 h |
0vs2 h |
0vs6 h |
|||||
1 |
acyl-Coenzyme A dehydrogenase |
ACADVL |
37 |
0.029 |
-1,18 |
1,37 |
1,01 |
1,12 |
2 |
CYP4F3 |
CYP4F3 |
4051 |
0.012 |
1,11 |
1,20 |
1,14 |
1,12 |
3 |
ERK |
MAPK1 |
5594 |
0.035 |
-1,08 |
-1,09 |
1,11 |
1,05 |
Genes significantly changed in OG + LTT compared to control challenge
| ||||||||
# |
Name |
Symbol |
GeneId |
p |
OG + LTT |
Control |
||
0vs2 h |
0vs6 h |
0vs2 h |
0vs6 h |
|||||
1 |
CCR2 |
CCR2 |
729230 |
0.021 |
1,02 |
-1,09 |
-1,11 |
-1,02 |
2 |
Mgl CD301 |
CLEC10A |
10462 |
0.002 |
-1,17 |
-1,01 |
-1,09 |
1,18 |
3 |
ITGAL CD11a |
ITGAL |
3683 |
0.041 |
-1,10 |
-1,10 |
1,02 |
1,05 |
5 |
IL-18 |
IL18 |
3606 |
0.029 |
-1,01 |
1,12 |
-1,18 |
-1,14 |
6 |
CD162 - P-selectin ligand |
SELPLG |
6404 |
0.027 |
1,05 |
-1,09 |
1,07 |
-1,05 |
7 | carnitine-acylcarnitine translocase | SLC25A20 | 788 | 0.041 | 1,08 | 1,11 | -1,25 | 1,22 |
Significance is based on repeated measurements.