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Multi-screening with mediator compounds. Landscapes from the HTS of the mutagenic library obtained from 3A4 HRPL using 2 mM syringaldehyde (A), 2 mM acetosyringone (B) and 20 mM violuric acid (C). Laccase activities of the clones are depicted in descending order respecting the activity of the parent type. Direct correlation of the activities of the clones explored by the triple screening is shown in the 3D landscape (D).
