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. 2014 May 9;9(5):e96780. doi: 10.1371/journal.pone.0096780

Table 2. The effect of different active extracts on cell viability, cellular antioxidant enzymes (Cu/Zn-SOD, Mn-SOD, GSH-Px and CAT) activities and MDA content in MRC-5 cells subjected to H2O2-induced oxidative stress.

Cell viability (%) Cu/Zn-SOD (U/mL) Mn-SOD (U/mL) GSH-Px (U/mL) CAT (U/mL) MDA (µM)
Control 100.00±0.552a 16.138±0.074a 6.703±1.411a 17.143±1.276a 5.199±0.077a 1.667±0.112f
H2O2 57.247±0.288g 7.469±0.222g 0.999±0.428d 3.158±0.638d 0.248±0.032e 8.889±0.224a
VE+H2O2 68.726±0.521e 8.826±0.369f 4.706±0.652bc 9.925±1.276c 2.010±0.160d 5.316±0.112c
CF-AME+H2O2 67.058±0.185f 9.558±2.221e 5.014±0.521b 5.414±1.276d 1.852±0.064d 7.222±0.114b
A1+H2O2 83.509±0.236b 12.691±0.074b 3.259±0.019c 13.083±0.638b 3.568±0.064b 3.730±0.112e
E1+H2O2 77.669±0.352c 12.012±0.148c 4.998±0.316b 10.827±1.276bc 3.500±0.032b 4.841±0.337d
TS#(A1+CF-AME+H2O2) 75.283±0.173d 11.124±0.148d 4.136±0.270bc 9.248±0.318c 2.710±0.001c 5.476±0.116c

Data were means ± standard deviation (n = 3).

a-g

Different letters within the same column indicated that means were statistically different at P<0.05.

#

TS: the theoretical sum of the antioxidant enzyme activity or MDA content of respective constituent extract with their proportion being 1:1 in the combinations.