Table 1.
Baseline Characteristics.
| Characteristics | All Subjects (n=562) | |
|---|---|---|
| Age (yrs) | 45.8 ± 0.5 | |
| Gender – #(%): | ||
| Female | 225 (40.0) | |
| Male | 337 (60.0) | |
| Race – #(%): | ||
| Caucasian | 462 (82.4) | |
| African-American | 77 (13.7) | |
| Other | 22 (3.9) | |
| Diabetic – #(%) | 52 (9.3) | |
| Hypertensive – #(%) | 334 (59.4) | |
| Current Smoker – # (%) | 31 (5.5) | |
| Total Cholesterol (mg/dL) | 182.7 ± 2.0 | |
| HDL Cholesterol (mg/dL) | 43.0 ± 0.7 | |
| LDL Cholesterol (mg/dL) | 107.3 ± 1.6 | |
| Screening Serum Creatinine (mg/dL) | 0.98 ± 0.01 | |
| eGFR (mL/min)((CKD-EPI) | 86.8 ± 0.8 | |
| eGFR (mL/min) (MDRD) | 79.7 ± 0.8 | |
| SASSI | 0.36 ± 0.01 | |
| LIB Diet | RES Diet | |
| BMI (kg/m2) | 27.7 ± 0.2 | 27.1 ± 0.2 |
| SBP (mmHg) | 133.1 ± 1.0 | 120.3 ± 0.8 |
| DBP (mmHg) | 79.7 ± 0.6 | 73.5 ± 0.5 |
| Urine Sodium (mmol/24hr)* | 231 (88) | 11 (11.1) |
| Aldosterone (ng/dL)* | 3.2 (3.3) | 14.5 (12.9) |
| PRA (ng/mL·h)* | 0.3 (0.4) | 1.9 (2.4) |
| Basal RPF (mL/min) | 518.4 ± 4.9 | 497.7 ± 5.1 |
Characteristics are shown for the total population used in the primary analyses. Parameters that varied depending on liberal sodium (LIB) or restricted sodium (RES) diets appear in the corresponding divided columns. Values are presented as mean ± SEM unless otherwise indicated.
*
Denotes median(IQR) and is presented for variables that are not normally distributed. SASSI indicates Sodium-modulated Aldosterone Suppression-Stimulation Index; eGFR, estimated Glomerular Filtration Rate; BMI, Body Mass Index; PRA, Plasma Renin Activity; and RPF, Renal Plasma Flow.