Table 2.
Aldosterone Dysfunction as a Predictor of Renal Plasma Flow (RPF): Stratified by Median Age.
| Regression Model | Age ≤ Median | Age > Median | ||
|---|---|---|---|---|
| β | p | β | p | |
| Unadjusted | +21.9 | 0.44 | -62.2 | 0.003 |
| Model 1 | +52.4 | 0.06 | -56.1 | 0.01 |
| Model 2 | +34.7 | 0.23 | -46.9 | 0.02 |
| Model 3 | +49.5 | 0.10 | -35.3 | 0.08 |
Effect estimates (β) and probability values (p) are presented for the relationship between SASSI and basal renal plasma flow in univariate and multivariate models. Model 1 is adjusted for age. Model 2 additionally adjusts for race, gender, body mass index, and the presence of diabetes. Model 3 additionally adjusts for systolic blood pressure. In those participants older than the median (47 years), there is a significant inverse association between SASSI and RPF that is significant through multivariate adjustment until systolic blood pressure is added.