Table 6. Analysis of the trajectories shown in Figure 7.

	# Pulse skipping	# Multiple budding	Total # cycles
D (90 min period)	0 (0)	-	11 (8)
M (90 min period)	-	4(2)	15 (10)
D (78 min period)	2 (0)	-	10 (8)
M (78 min period)	-	2(1)	15 (10)
D (69 min period)	3 (1)	-	11 (8)
M (69 min period)	-	0 (0)	14 (10)
D (no forcing)	-	-	10 (7)
M (no forcing)	-	-	15 (10)

Shown is the number of budding events that show lack of synchrony with the pulse for mother (M) or daughter (D) cells in 1000 min simulations. The number of observations until 700 min is shown in parentheses. Pulse skipping happens when the cell does not bud between two subsequent pulses, whereas observing multiple budding events between subsequent pulses is a consequence of the natural cycle time (with no forced CLN2 expression) being significantly shorter than the forcing period. The total number of cycles without forced CLN2 expression (cln3) is given in the last two rows for daughters and mothers, respectively. The numbers of pulse skipping events, multiple budding events, and total number of cycles are computed from a single mother or daughter trajectory per forcing period.