Table 4.
The Iowa Proctectomy Risk Model. Shown are included predictive variables with associated odds-ratios (OR) for morbidity, 95% confidence intervals (CI), and P values.
| Variable | OR | 95% CI | P Value |
|---|---|---|---|
| Primary procedure (APR reference) | 1.00 | - | <0.001 a |
| Lap APR | 0.74 | 0.58-0.93 | <0.01 |
| Lap proctectomy with j-pouch, coloanal anastomosis, pos. stoma | 0.59 | 0.44-0.78 | <0.001 |
| Lap proctopexy with sigmoid resection | 0.18 | 0.06-0.42 | <0.001 |
| Lap TPC ileostomy | 0.81 | 0.60-1.10 | 0.18 |
| Lap TPC IPAA pos. ileostomy | 0.68 | 0.53-0.87 | <0.01 |
| Pelvic exenteration | 2.53 | 1.51-4.37 | <0.001 |
| Proctectomy | 0.51 | 0.40-0.64 | <0.001 |
| Proctectomy with j pouch, coloanal anastomosis, pos. stoma | 0.73 | 0.56-0.95 | 0.018 |
| Proctectomy IPAA pos. ileostomy | 0.77 | 0.58-1.02 | 0.068 |
| Proctectomy with anastomosis | 0.60 | 0.46-0.78 | <0.001 |
| Proctopexy with sigmoid resection | 1.08 | 0.56-2.07 | 0.81 |
| TPC IAA pos. ileostomy | 0.61 | 0.42-0.88 | <0.01 |
| TPC ileostomy | 0.91 | 0.73-1.14 | 0.41 |
| TPC IPAA pos. ileostomy | 0.76 | 0.58-0.99 | 0.041 |
| Transsacral proctotomy | 0.23 | 0.08-0.56 | <0.01 |
| Age | 1.006 | 1.002-1.010 | <0.01 |
| Smoking | 1.30 | 1.12-1.52 | <0.001 |
| Dyspnea at rest or with exertion | 1.57 | 1.23-2.02 | <0.001 |
| Poor functional status | 1.36 | 0.95-1.95 | 0.091 |
| History of stroke | 2.01 | 1.13-3.66 | 0.02 |
| Disseminated cancer | 1.69 | 1.29-2.21 | <0.001 |
| Preoperative open wound | 1.79 | 1.25-2.57 | <0.01 |
| Preoperative steroid/immunosuppressant use | 1.25 | 1.04-1.52 | 0.02 |
| Preoperative weight loss >10% | 1.28 | 1.01-1.64 | 0.042 |
| Transfusion of >4U PRBC in 72 hours prior to surgery | 2.51 | 1.37-4.88 | <0.01 |
| Radiation therapy within 90 days | 0.83 | 0.69-0.98 | 0.031 |
| Preoperative sepsis | 1.40 | 0.93-2.13 | 0.11 |
| INR checked within 30 days | 1.19 | 1.06-1.33 | <0.01 |
| Preoperative leukocyte count | 1.02 | 1.002-1.04 | 0.033 |
| Preoperative hematocrit | 0.95 | 0.93-0.96 | <0.001 |
| BMI Category (Normal; BMI 18.5-24.9 reference) | 1.00 | - | <0.001 a |
| Underweight; BMI <18.5 | 0.90 | 0.66-1.21 | 0.47 |
| Overweight; BMI 25-29.9 | 1.04 | 0.90-1.20 | 0.60 |
| Class I Obesity; BMI 30-34.9 | 1.38 | 1.16-1.64 | <0.001 |
| Class II Obesity; BMI 35-39.9 | 1.97 | 1.55-2.51 | <0.001 |
| Class III Obesity; BMI 40 or greater | 1.42 | 1.03-1.95 | 0.031 |
APR: Abdominoperineal resection; Lap: Laparoscopic; Pos.: Possible; TPC: Total Proctocolectomy; IPAA: Ileal-Pouch-Anal-Anastomosis; IAA: Ileal-Anal-Anastomosis; U PRBC: Units Packed Red Blood Cells
a
These p-values represent overall significance of Primary Procedure and BMI Category variables.