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. 2014 May 9;9(5):e96943. doi: 10.1371/journal.pone.0096943

Table 1. Effects of PTPN22 SNPs on VKH syndrome risk.

Genotype VKH Controls P value Pc value OR (95%CI)
N = 1005 N = 2010
rs2488457 N % N %
GG 102 10.1 310 15.4 7.06×10−5 6.35×10−4 0.62(0.49–0.79)
CG 454 45.2 1009 51.2 0.009 NS 0.82(0.70–0.95)
CC 449 44.7 691 34.4 3.86×10−8 3.47×10−7 1.54(1.32–1.80)
G Allele 658 32.7 1629 40.5 4.25×10−9 3.83×10−8 0.71(0.64–0.80)
C Allele 1352 67.3 2391 59.5 4.25×10−9 3.83×10−8 1.40(1.25–1.57)
rs1310182
CC 48 4.8 84 4.2 0.450 NS 1.15(0.80–1.65)
CT 292 29 589 29.3 0.887 NS 0.99(0.84–1.17)
TT 665 66.2 1337 66.5 0.849 NS 0.99(0.84–1.16)
C Allele 388 19.3 757 18.8 0.659 NS 1.03(0.90–1.18)
T Allele 1622 80.7 3263 81.2 0.659 NS 0.97(0.85–1.11)
rs3789604
TT 648 64.5 1254 62.4 0.262 NS 1.09(0.94–1.28)
GT 303 30.1 651 32.4 0.231 NS 0.90(0.77–1.06)
GG 54 5.4 105 5.2 0.863 NS 1.03(0.74–1.44)
T Allele 1599 79.6 3159 78.6 0.384 NS 1.06(0.96–1.21)
G Allele 411 20.4 861 21.4 0.384 NS 0.94(0.83–1.08)

Pc = Bonferroni corrected P value. NS = Not significant. OR = odds ratio. 95% CI = 95% confidence interval.