Table 2.

Variables associated with decreased total medication use over time for four time periods

Variable	Baseline to 6 mo. (n=353)	Baseline to 12 mo. (n=277)	6 months to 12 mo. (n=230)	Baseline to last endpointc (n=400)
Age (continuous)	1.024 (1.001–1.047)	-	1.031 (1.001–1.062)	-
Male (v. female)	-	2.427 (1.078–5.464)	-	-
Roux-en-Y gastric bypass (v. laparoscopic banding)	1.978 (1.203–3.253)	-	-	1.738 (1.096–2.755)
Baseline hypertension	1.970 (1.167–3.327)	-	-	2.432 (1.545–3.829)
Baseline type 2 diabetes	2.693 (1.635–4.438)	5.096 (2.780–9.339)	3.064 (1.541–6.093)	3.226 (1.996–5.216)
Baseline GERDd	1.960 (1.223–3.143)	2.388 (1.370–4.161)	-	2.236 (1.431–3.494)
Baseline asthma	-	4.154 (1.336–12.913)	2.797 (1.104–7.086)	-

^aData presented as odds ratio (95% confidence interval)

^b- indicates no association at p≤0.05

^cLast endpoint is either 6 or 12 months post-operative depending on the patient’s post-operative appointment attendance

^dGERD= Gastroesophageal reflux disease