Table 6.

Gene- and pathway-level summary p-values from ARTP pathway analyses in LABCS and SBCS

Pathway	Gene/Region	ARTP Gene p-value							ARTP Pathway p-value
		NHW			Chinese			Combined	NHW			Chinese			Combined
BER		All	Females	Males	All	Females	Males	All	All	Females	Males	All	Females	Males	All
									0.746	0.443	0.4845	0.356	0.143	0.329	0.724
	APEX1	0.926	0.932	0.898	0.831	0.920	0.791	0.926
	LIG3	0.431	0.061	0.904	0.834	0.891	0.767	0.474
	NEIL1	0.633	0.727	0.712	0.881	0.922	0.724	0.894
	OGG1	0.674	0.678	0.812	0.225	0.015	0.556	0.486
	PARP1	0.170	0.650	0.066	0.895	0.085	0.761	0.628
	POLB	0.416	0.248	0.980	0.010	0.262	0.048	0.013
	XRCC1	0.736	0.252	0.828	0.209	0.887	0.116	0.694
HRR									0.554	0.587	0.784	0.510	0.772	0.219	0.676
	MRE11A	0.272	0.239	0.285	0.805	0.589	0.849	0.566
	NBN	0.380	0.310	0.366	0.471	0.718	0.651	0.795
	RAD50	0.591	0.189	0.871	0.034	0.824	0.023	0.048
	RAD51	0.214	0.923	0.196	0.930	0.965	0.970	0.402
	RAD52	0.967	0.488	0.959	0.821	0.622	0.946	0.935
	XRCC2	0.154	0.267	0.466	0.779	0.155	0.978	0.276
	XRCC3	0.384	0.872	0.877	0.321	0.395	0.255	0.664
NER									0.649	0.672	0.234	0.068	0.293	0.034	0.107
	ERCC1-ERCC2	0.682	0.824	0.740	0.133	0.161	0.193	0.087
	ERCC4	0.312	0.2105	0.918	0.069	0.160	0.267	0.487
	ERCC5	0.177	0.7625	0.181	0.332	0.916	0.462	0.360
	LIG1	0.139	0.3745	0.025	0.716	0.302	0.795	0.942
	POLD1	0.430	0.4705	0.315	0.021	0.057	0.105	0.013
	XPA	0.956	0.1245	0.985	0.915	0.491	0.806	0.886
	XPC	0.563	0.9705	0.440	0.017	0.941	0.003	0.045
NHEJ									0.598	0.182	0.698	0.236	0.206	0.774	0.397
	DCLRE1C	0.975	0.190	0.7845	0.728	0.216	0.942	0.717
	LIG4	0.715	0.241	0.841	0.908	0.711	0.935	0.841
	PRKDC	0.587	0.352	0.7015	0.789	0.298	0.840	0.540
	XRCC4	0.104	0.125	0.140	0.174	0.247	0.315	0.129
	XRCC5	0.768	0.629	0.678	0.292	0.333	0.280	0.595
	XRCC6	0.821	0.076	0.808	0.038	0.043	0.284	0.458