Table 2. Final triple reporter tumor optical signals in vivo and weights ex vivo following therapy.

	Untreated average (n = 10)	MMAF average (n = 10)	MMAE average (n = 10)
Weight (mg)	885.9±416.2	878.3±536.7	29.8±21.4*
Total fluorescence [(p/s)/(cm2/sr)]	8.5×108±3.4×108	8.4×108±4.1×108	2.6×107±3.3×107*
Total bioluminescence (p/s)	1.4×109±8.9×108	1.3×109±9.8×108	2.8×107±2.1×107*
Caliper-estimated size (mm3)	393.7±237.8	413.4±245.7	Sub-palpable*

Tumors from the therapy experiment were imaged then resected and weighed after 28 days of growth in vivo. Optical signals of the triple reporter tumors were representative of the tumor mass. Tumors in the MMAE-treated group were too small to be measured by a caliper after day 19. Significant decreases (p<0.005) in the tumor weight and optical signals in the MMAE-treated group compared to the untreated and MMAF-treated groups are indicated by*.