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. 2014 Mar 6;11:42. doi: 10.1186/1742-2094-11-42

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Copyright © 2014 Cui et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparison of Cx mRNA expression levels in mSOD1-Tg and non-Tg mice by quantitative real-time PCR. (A) At 12 weeks of age, the relative expression level of Cx43 mRNA in mSOD1-Tg mice is significantly increased compared with that in non-Tg mice. (B) At 18 weeks of age, the expression level of Cx47 mRNA is significantly decreased in mSOD1-Tg mice. (C) At 20 weeks of age, the expression level of Cx43 mRNA is significantly increased in mSOD1 mice, whereas that of Cx32 is significantly decreased. In addition, the expression level of Cx47 mRNA shows a decreased tendency in mSOD1-Tg mice. (*P < 0.05, **P < 0.001).