Table 1.
Clinical and histopathological features of pediatric patients with embryonal rhabdomyosarcoma (RMS) (n=19)
| Embryonal RMS n (%) | |
|---|---|
| Sex |
|
| Male |
11 (58) |
| Female |
8 (42) |
| Age (years) |
|
| < 10 |
14 (74) |
| ≥ 10 |
5 (26) |
| Localisation |
|
| Orbit-genitourinary tract-head and neck$ |
9 (47) |
| Cranial paramenigeal-extremity-other$$ |
10 (53) |
| Tumor volume |
|
| < 5 cm |
7 (37) |
| ≥ 5 cm |
12 (63) |
| IRS stage |
|
| I |
2 (10) |
| II |
3 (16) |
| III |
11 (58) |
| IV |
3 (16) |
| Metastasis |
|
| No |
16 (84) |
| Yes |
3 (16) |
| Recurrence |
|
| No |
12 (63) |
| Yes |
7 (37) |
| Outcome |
|
| Alive |
13 (68) |
| DOD |
6 (32) |
| Expression of markers |
|
| EZH2 (positive cells/microscopic field) |
40 (range 29-44) |
| Ki67 (positive cells/microscopic field) | 20 (range 17-29) |
Abbreviations: DOD dead of disease, IRS Intergroup Rhabdomyosarcoma Study Group staging system.
$Favorable and $$Unfavorable tumor localization.