Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb 18;14:105. doi: 10.1186/1471-2407-14-105

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Yang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Summarized dose–response association between dietary ratio of n-3/n-6 PUFAs and risk of breast cancer. Adjusted RRs from each exposure quantile of dietary ratio of n-3/n-6 PUFAs in included individual studies were represented by the gray diamonds, and corresponding intervals (CIs) were represented by the lightgray trendline. The dash line indicated that dose–response linear trend (P_trend = 0.012) between dietary ratio of n-3/n-6 PUFAs and risk of breast cancer by use of variance-weighted least squares regression of fixed effect model; the black curve indicated nonlinear (curvilinear) trend (P_trend = 0.018) by use of restricted cubic splines functional model with three knots at percentiles 25%, 50%, and 75% of the distribution.