Table 1.
Relationship between miR-25 expression level and clinicopathologic parameters of hepatocellular carcinoma
| Factor | No. | miR-25 expression | P value |
|---|---|---|---|
| Gender |
|
|
|
| Male |
81 |
8.34 ± 4.85 |
|
| Female |
50 |
8.11 ± 4.63 |
0.62 |
| Age at diagnosis(year) |
|
|
|
| ≤50 |
53 |
8.01 ± 5.11 |
|
| >50 |
78 |
8.49 ± 3.89 |
0.21 |
| Tumor size(cm) |
|
|
|
| ≤5 |
62 |
7.99 ± 5.13 |
|
| >5 |
69 |
9.01 ± 3.79 |
0.13 |
| Tumor number |
|
|
|
| Solitary |
70 |
8.13 ± 4.34 |
|
| Multiple |
61 |
8.57 ± 4.89 |
0.51 |
| TNM stage |
|
|
|
| I-II |
72 |
6.34 ± 3.12 |
|
| III-IV |
59 |
11.01 ± 5.61 |
0.01 |
| Vein invasion |
|
|
|
| Presence |
79 |
9.12 ± 4.89 |
|
| Absence |
52 |
7.31 ± 4.19 |
0.24 |
| Cirrhosis |
|
|
|
| Negative |
44 |
7.12 ± 3.19 |
|
| Positive |
87 |
8.89 ± 5.38 |
0.17 |
| Hepatitis B virus infection |
|
|
|
| Negative |
42 |
6.17 ± 4.65 |
|
| Positive |
89 |
9.21 ± 4.13 |
0.09 |
| Serum AFP level (ng/ml) |
|
|
|
| ≤25 |
54 |
6.02 ± 3.87 |
|
| >25 | 77 | 10.99 ± 5.44 | 0.02 |
AFP,α-fetoprotein.