Table 2.
multivariate analyses of prognostic factors in hepatocellular carcinoma
|
Variable |
Subset |
Overall survival |
||
|---|---|---|---|---|
| HR | 95% CI | P | ||
| miR-25 expression |
High/low |
2.179 |
1.876-4.335 |
0.001 |
| Gender |
Male/female |
0.982 |
0.901-1.003 |
0.652 |
| Age at diagnosis |
>50/≤50 |
1.231 |
0.922-1.523 |
0.212 |
| Tumor size |
>5/≤5 |
1.479 |
0.991-2.127 |
0.090 |
| Tumor number |
Multiple/solitary |
1.854 |
0.823-2.132 |
0.121 |
| TNM stage |
III-IV/I-II |
1.782 |
1.389-2.993 |
0.014 |
| Vein invasion |
Presence/absence |
1.624 |
1.233-1.981 |
0.020 |
| Cirrhosis |
Positive/negative |
1.027 |
0.876-1.535 |
0.320 |
| Hepatitis B virus infection |
Positive/negative |
1.002 |
0.892-1.337 |
0.417 |
| Serum AFP level | >25/≤25 | 1.377 | 0.882-1.335 | 0.398 |
CI, confidence interval; HR, hazard ratio; miR-25, microRNA-25.