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. 2014 Apr 24;9:96. doi: 10.1186/1748-717X-9-96

Figure 2.

Figure 2

Comparison of gastrointestinal toxicity ≥ Grade 2 with other trials. Lips et al. [18]: PTV = Prostate + seminal vesicles + 8 mm margin, 76 Gy mean dose, not more than 5% of rectum received ≥ 72 Gy. Vora et al. [19]: PTV = Prostate + seminal vesicles + 6-10 mm margin, 50.4 Gy + Boost (median 75.6 Gy), not more than 40%/30%/10% of Rectum received ≥ 65 Gy/70 Gy/75 Gy, not more than 1.8 cm2 of rectum received 81 Gy. Zietman et al. [8]: PTV = Prostate + seminal vesicles + 10 mm margin for Photontherapy (50.4 Gy) and 5mm margin for proton Boost (28.8 GyE).